Prof. Christopher Salthouse

Dr. Salthouse received bachelor's, master's, and doctoral degrees from the Massachusetts Institute of Technology. During his doctoral work in Prof. Sarpeshkar's lab, he developed micropower integrated circuits for cochlear implants (biomedical devices that give hearing to the deaf). He then moved to Massachusetts General Hospital in the Center for Systems Biology where he worked on cell culture and mouse models of human disease and developed a variety of fluorescence imaging systems. He now directs the Biomedical Electronics Laboratory at the University of Massachusetts.

Recent Publications

H. Wang, Y. Qi, T. J. Mountziariz, and C. D. Salthouse, "A portable time-domain LED fluorimeter for nanosecond Fluorescence lifetime measurements", Review of Scientific Instruments, vol. 85, no. 5, p. 055003, May 2014

C.D.Salthouse, A.Shanmugam, 'Lensless Fluorescence Imaging Systems to Measure Surface Sample Flow', 225th Electro Chemical Society Meeting, 2014

A.Shanmugam, C.D.Salthouse, 'Microfluidic on CMOS with laser Cut Adhesive Tape', 225th Electro Chemical Society Meeting, 2014

Li, Shuo, and Christopher Salthouse, "Digital-to-time converter for fluorescence lifetime imaging." Instrumentation and Measurement Technology Conference (I2MTC), 2013 IEEE International. IEEE, 2013

A.Shanmugam, C.D.Salthouse, 'Lensless Fluorescence Imaging with Height Calculation', Journal of Biomedical Optics, 19(1):016002, 2013

A.Shanmugam, C.D.Salthouse, 'Miniaturized On-Sensor Fluorescence Flow Cytometer', IEEE Sensors, pp. 1-4, Oct 2012

A.Shanmugam, C.D.Salthouse, '3D Lensless Fluorescence Imaging', I2MTC, pp. 1109-1112 May 2012

A.Shanmugam, K.Okiah, C.D.Salthouse, 'Lensless Fluorescence Imaging of Flowing Beads in Microfluidics', The Electrochemical Society, 2012

S. Hildebrand, F. Shao, C. Salthouse, U. Mahmood, and R. Weissleder, "Upconverting Luminescent Nanomaterials: Application to in vivo Bioimaging" Chemical Communications preprint online

C. Salthouse, F. Reynolds, J. Tam, L. Josephson, and U. Mahmood, "Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects" Sensors and Actuators B: Chemical, vol. 138, no. 2, pp. 591-597, May 2009.

C. Salthouse, S. Hildebrand, R. Weissleder, and U. Mahmood, "Design and Demonstration of a Small-Animal Up-Conversion Imager" Optics Express, vol. 16, no. 26, pp. 21731-21737, December 2008.

C. Salthouse, R. Weissleder, and U. Mahmood "Development of a Time Domain Fluorimeter (TDF) for Fluorescent Lifetime Multiplexing Analysis" IEEE TBCAS, vol. 2, iss. 3, pp. 204-211, Sept. 2008

C. Salthouse, R. Upadhyay, R. Weissleder, and U. Mahmood, "In Vivo Discrimination of Two Far Red Dyes with Identical Absorption and Emission Spectra Based on Fluorescent Lifetime for Improved Multiplexing" presented at the Radiological Society of North America November 2007.

C. Salthouse, R. Upadhyay, R. Weissleder, and U. Mahmood, "Fluorescent Lifetime Discrimination of Activatable Probe Signal from Autofluorescence in Whole Mouse Imaging" presented at the Joint Society for Molecular Image / Academy of Molecular Imaging Conference September 2007.

C. D. Salthouse and R. Sarpeshkar, "Jump Resonance: A Feedback And Adaptive Circuit Solution For Low-Power Active Analog Filters," IEEE TCAS-I, vol. 53, iss. 8, pp. 1712-1725, Aug. 2006.

C. D. Salthouse and R. Sarpeshkar, "A Practical Micropower Programmable Bandpass Filter For Use in Bionic Ears," IEEE J. Solid-State Circuits, vol. 38, iss. 1, pp. 63-70, Jan. 2003.

C. D. Salthouse and R. Sarpeshkar, "A Micropower Band-Pass Filter For Use in Bionic Ears," IEEE International Symposium on Circuits and Systems 2002 (ISCAS), Vol. 5 pp. V-189-V-192, May 2002.

R. Sarpeshkar, C. Salthouse, JJ Sit, M.W. Baker, S. M. Zhak, T.K.-T. Lu, L. Turiccia, and S. Balster, "An Ultra-Low-Power Programmable Analog Bionic Ear Processor," IEEE Transactions on Biomedical Engineering, vol. 52, iss. 4, pp. 711-727, April 2005.