David Langenau, Ph.D.

Dr. Langenau is an Assistant Professor at Harvard Medical School and runs a lab in the Molecular Pathology/Cancer Center at Massachusetts General Hospital. His research focuses on using the zebrafish to better understand human cancer and develop novel insights into how it is that tumors can be remade following conventional chemotherapeutic intervention. Projects center on using cutting-edge live cell imaging to visualize tumor development in fluorescent-labeled zebrafish solid tumors and leukemia. Additionally, cell transplantation of tumor cells is commonly used to study cancer stem cells and self-renewal. Using conditional transgenic approaches and chemical genetics we are interrogating which pathways are used for cancer stem cell self-renewal and tumor growth.